盐酸莫西沙星治疗急性盆腔炎的临床观察

Study on the efficacy of moxifloxacin hydrochloride tablets in treatment of acute pelvic inflammatory disease

目的:观察盐酸莫西沙星治疗急性盆腔炎的临床疗效。方法:研究对象随机分为两组,各25例,治疗组口服盐酸莫西沙星400 mg每日1次;对照组头孢曲松钠0.25 g肌注,每日1次,希舒美0.5 g口服,每日1次,两组均治疗14 d。结果:治疗组口服治疗轻型急性盆腔炎临床治愈率高达92%,无临床失败病例,42 d回访无复发病例。对照组临床治愈率80%,1例临床失败病例,42 d回访3例复发。两组症状体征积分比较,差异具有统计学意义(P<0.05)。治疗组副作用轻。结论:盐酸莫西沙星临床用药方便,疗效好,副反应轻,值得临床推广。

Objective： To observe efficacy of moxifloxacin hydrochloride tablets in the treatment of acute pelvic inflammatory disease. Methods： The subjects were randomly divided into treating group and control group 25 cases, respectively. In the treating group ,subjects took moxifloxacin hydrochloride tablets 400 mg Qd for 14 days, and in the control group, they received ceftriaxone sodium injection 0.25g im Bid and took zithromax tablets 0.5g Qd for 14 days. Results： The rate of cure was 92%, no fail cases and following up after 42 days no recrudescent cases , in treating group. However, the rate of cure was 80% in control group with 1 fail cases and 3 recrudescent cases. There were significant differences between two groups about integral of symptoms and signs （P〈0.05）. The treating group was better and no serious adverse events. Conclusion： moxifloxacin hydrochloride Tablets are convenient, effective, no serious adverse events, and valuable to popularize use.