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前列腺素类化合物化学全合成研究现状 被引量：2

Recent Progress in Total Synthesis of Prostaglandins
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摘要 综述近年来前列腺素类化合物全合成研究的新进展以及对新药研发的推动作用。前列腺素是一类重要的具有多种生物活性且低毒性的内源性天然产物,在医药领域用途广泛,其全合成研究也备受关注,并取得长足发展。 The recent advances in the research of total synthesis of prostagladins and the driving effect thereof on drug discovery were reviewed. Prostaglandins are the important kind of endogenous natural products with multiple bioactivities and low toxicity and widely used in the medical field. So the research of total synthesis has has aroused the interest of all and made a great progress.
作者 侯英伟 孙宏斌
机构地区 中国药科大学新药研究中心
出处 《药学进展》 CAS 2009年第9期408-415,共8页 Progress in Pharmaceutical Sciences
关键词 前列腺素 全合成 Corey内酯 prostaglandins total synthesis Corey lactone
分类号 R914 [医药卫生—药物化学]
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参考文献20

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同被引文献38

  • 1齐创宇,何煦昌.前列腺素关键中间体——手性Corey Lactone的合成研究进展[J].合成化学,2006,14(6):539-545. 被引量：4
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药学进展
2009年 第9期

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