佛山口岸出入境人员抗-HCV和ALT检测结果分析

The Analysis of Anti-HCV and ALT among International Travelers at Foshan Port

目的了解佛山口岸出入境人员丙型肝炎病毒感染情况及丙氨酸转氨酶(ALT)的异常情况,以加强对出入境人员丙型肝炎病毒感染的监测和管理。方法对2006-2007年佛山口岸出入境人员进行抗-HCV和ALT检测,并对检测结果进行统计分析。结果在2919名受检者中检出抗-HCV阳性15例,检出率为5.14‰,入境人员阳性率1.38%,明显高于出境人员阳性率0.15%,两者之间有显著性差异(χ2=15.86,P<0.05);其中入境人员中劳务、商务人员分别占总阳性数的66.67%和33.33%。抗-HCV阳性者ALT异常率为66.67%,抗-HCV、HBsAg阴性者ALT异常率为8.22%,HB-sAg阳性者ALT异常率为23.67%,抗-HCV阳性者ALT异常率与后两者异常率比较分别为(χ2=57.81,P<0.05)和(χ2=11.81,P<0.05),差异有统计学意义。结论抗-HCV阳性者ALT异常情况更明显。应加强管理抗-HCV阳性的出入境人员,做好宣传教育并提供有效的医疗服务,以减少丙型肝炎通过频繁的国际交往而传播的机会,有效保障出入境人员的健康。

Objective Strengthen the supervision and administration of the hepatitis C virus infection among international travelers by studying the HCV infection and Alt abnormity at Foshan port.Methods Anti-HCV and ALT tests were conducted among international travelers at Foshan port from 2006 to 2007 and the results were analyzed in a statistical way.Results 15 cases of anti-HCV positive were detected among 2919 subjects, with a rate of 5.14‰ among which the detectable rate of incoming personnel was 1.38 %, evidently higher than 0.15 %, the of the outbound. There was evident difference between both numbers（X^2=15.86,P〈0.05）. Among the incoming personnel, labors and business personnel respectively account for 66.67 % and 33.33 %. The abnormal rate of ALT among the anti-HCV positive cases was 66.67 %, 8.22 % among the anti-HCV, HBsAg negative cases, and 23.67 % among the HBsAg positive cases. There was evident difference between anti-HCV positive cases and the latter two （X^2=57.81,P〈0.05）,（X^2=11.81,P〈0.05）. Conclusion ALT abnormity is more evident among the anti-HCV positive cases. Administration of anti-HCV positive international travelers should be strengthen and effective medical service should be provided to reduce communication of hepatitis C and protect people＇s health.