摘要
目的:探讨直肠癌根治术后肺转移的治疗效果和影响预后的因素。方法:回顾性分析1978~2008年间的直肠癌根治术后发生单纯性肺转移的72例病例资料。结果:自原发灶切除术后全组病例中位生存时间34个月,行转移灶的切除手术23例,中位生存49个月;其余49例行非手术治疗,中位生存33个月;其中转移瘤大于3个组中位生存时间28个月,转移瘤小于等于3个组中位生存时间41个月。手术患者和转移灶个数少的患者的总生存率较大,总生存率可能和是否手术、转移灶的个数有关,但尚未发现年龄、性别、原发灶病理类型、分期、转移灶大小对生存率有明显影响。结论:直肠癌肺转移灶的手术治疗是安全、有效的。手术及转移灶个数可影响患者生存率。
Objective: This study was to investigate the features, treatments and prognostic factors of patients with lung metastatic diseases after resection of rectal cancer. Methods: Clinical data of 72 patients who suffered lung metastatic diseases after received radical resection of rectal cancer in 1978-2008, were rospectively analyzed. Results: The median survival time after the primary disease opera- tion is 34 months. The median survival time of 23 cases who had received lung operation is 49 months, the nonoperation patients' is 33 months. The median survival time of patients with more than 3 metastatic diseases in the lung is 28 months, the other patients is 43 months. The overall survival time was probably associated with operations of the lung and the number of metastatic diseases, and the oth- er factors were of no significance. Conclusion: The active treatment for lung metastasis after rectal cancer operation is effective. The op- eration and the number of metastasis may be the factors that can influence the patients prognosis.
出处
《现代生物医学进展》
CAS
2009年第15期2887-2888,2931,共3页
Progress in Modern Biomedicine
关键词
直肠癌
肺转移
手术
rectal cancer
lung metastasis
operation