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灰区淋巴瘤的临床病理分析 被引量：6

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摘要 目的探讨灰区淋巴瘤(grey zone lymphoma,GZL)的概念、临床及病理组织学特征。方法应用光镜观察及免疫组化染色对2例纵隔GZL的病例进行临床病理学分析,同时复习相关文献。结果例1组织学形态提示纵隔大B细胞性淋巴瘤(PMBL),CD20+,但免疫表型呈经典型霍奇金淋巴瘤(CHL)的特点,表达CD15和CD30;病例2组织学提示结节硬化型CHL,但免疫表型提示为DLBCL,CD20+,CD30+。结论GZL是一种独特类型的淋巴瘤,存在两种形式,一种是组织学形态提示PMBL,但免疫表型呈CHL的特点,另一种是组织学提示CHL,但免疫表型提示为弥漫大B细胞性淋巴瘤(DLBCL)。两种过渡型病变具有连续性,难以区分CHL和PMBL。
作者 陈定宝 宋秋静 戴林
机构地区 北京大学人民医院病理科
出处 《临床与实验病理学杂志》 CAS CSCD 北大核心 2009年第4期422-425,共4页 Chinese Journal of Clinical and Experimental Pathology
关键词 纵隔淋巴瘤 灰区淋巴瘤 弥漫大B细胞性淋巴瘤 霍奇金淋巴瘤
分类号 R734.4 [医药卫生—肿瘤]
  • 相关文献

参考文献13

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二级参考文献60

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共引文献17

同被引文献49

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引证文献6

二级引证文献10

临床与实验病理学杂志
2009年 第4期

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