原发性肺癌并发肾损害临床分析

A clinical analysis of primary lung cancer complicated with renal lesions

目的分析原发性肺癌并发肾损害的发生率、临床特点、诊断、治疗。方法对我院有随诊资料的169例肺癌患者的临床资料进行回顾性分析。结果不同性别、年龄、组织病理学类型的肺癌并发肾损害的发生率无显著差别（P〉0．05），但不同分期的肺癌患者肾损害的发生率不同，与早期患者比较，晚期患者肾损害的发生率较高，二者之间的差异具有统计学意义（P〈0．05）。原发病治疗后24h尿蛋白定量显著减少，与治疗前比较，差异具有统计学意义（P〈0．05）。结论单纯性蛋白尿或血尿是原发性肺癌并发肾损害的主要临床表现。晚期肺癌患者容易发生肾损害。对原发性肺癌的有效治疗可缓解肾损害的程度。

Objective To analyze the incidence, clinical features,diagnosis, treatment of renal lesions in patients with primary lung cancer. Method The clinical data of 169 patients with lung cancer who had follow-up data in our hospital were analyzed retrospectively. Result The incidence of renal lesions in patients with lung cancer showed no significant difference in different gender, age and histological type（P〉0. 05）. However, the incidence of renal lesions was different among different stages of lung cancer： the incidence of renal lesions in later stage was higher （P〈0. 05）. After treatment of primary disease, the 24-h urinary protein was significantly reduced as compared with that before treatment （P〈0. 05）. Conclusion Simple proteinuria or hematuria is the main clinical manifestation of renal le- sions in patients with primary lung cancer. The advanced patients with lung cancer are prone to renal lesions. The renal lesions can he eased to some extent through the effective treatment of primary lung cancer.