摘要
目的探讨川芎浸膏真空带式干燥的最佳工艺条件。方法采用正交试验法,以干膏含水量和阿魏酸含量为考察指标,对影响川芎浸膏带式真空干燥过程的因素进行考察。结果川芎浸膏带式真空干燥的最佳工艺条件为加热区温度为95℃,进样速度为10Hzs/,履带速度为10Hz/s。结论采用真空带式干燥工艺干燥川芎浸膏,干燥速率高、产品质量好,符合GMP的要求,可为工业化生产提供依据。
Objective To explore the optimal conditions of the vacuum - belt drying process of Rhizoma Chuanxiong extract. Methods Influencing factors of the vacuum belt drying process of Rhizoma Chuanxiong extract were studied by using orthogonal test. The water content and ferulic acid content of dried product were used as the quality indicators. Results The optimal parameters of the vacuum -belt drying process were as follows： the heated region temperature being 95 ℃, the feeding speed at 10 Hz/s, and the belt speed atl0 Hz/s. Conclusion The vacuum - belt drying technique- for drying the extract brings high drying rate and high quality product. This study can provide a reasonable basis for industrial production in line with the GMP requirements.
出处
《中药新药与临床药理》
CAS
CSCD
北大核心
2009年第5期477-479,共3页
Traditional Chinese Drug Research and Clinical Pharmacology
基金
广东省关键领域重大突破(中药现代化)项目(2003A30905)
广州市科技攻关重大项目(2003Z1-E5021)
关键词
川芎
浸膏
真空带式干燥
正交试验
Rhizoma Chuanxiong
Extract
Vacuum -belt drying
Orthogonal test
