脑出血灶周水肿相关因素的临床分析

Clinical analysis of influencing factors on peripheral edema of cerebral hemorrhage

目的从临床角度探讨一般因素与灶周水肿的相关性。方法对80例符合标准的脑出血患者在入院时和发病后24h、72h、7d、14d分别进行神功能评分、头颅CT扫描,测量血肿、水肿体积,设置变量,在单因素分析的基础上进行多因素回归分析、方差分析。结果血肿大小、发病后持续的时间、出血部位、神经功能缺损程度、高血压均对脑出血后灶周水肿有不同程度的影响。入院时神经功能缺损程度、血肿大小、高血压的程度与灶周水肿呈正相关。灶周水肿在发病后缓慢增加,至72h到峰顶,此后开始缓慢下降。结论脑出血后灶周水肿与多种因素有关,早期应根据神经功能缺损程度、有无高血压史及血压增高程度、病程长短、血肿大小及部位等因素判断灶周水肿情况,选择防治脑水肿的手段及方法,同时注意脑水肿发生的高峰时间段。

Objective To study the impact of the general factors on peripheral edema from the clinical point of view. Methods Neurological deficit score,CT, haematoma, edema volume,ect, were studyed in 80 patients with brain hemorrhage on admission before treatment, 24h, 72h, 7d and 14d, in the single-factor analysis based on multi-factor regression and variance analysis. Results Hematoma size, duration after onset, bleeding site, the degree of neurological deficit, high blood pressure on the brain edema after intracerebral hemorrhage lesions had different degrees of impact. The degree of neurological deficit of admission, hematoma size, the degree of hypertension and edema lesions was positively correlated, brain edema up to the peak in 72h and slowly decline after it. Conclusion Peripheral edema were correlative with a variety of factors early stage should be based on the degree of neurological deficit, any history of hypertension, course length,the size of hematoma to determine the focal edema, select the method of prevention and treatment of cerebral edema, at the same time pay attention to the peak of brain edema in time.