隐形眼镜护理液中和剂鉴定试验

VERIFICATION TEST FOR NEUTRALIZER OF CONTACT LENS CARE SOLUTION

目的研究隐形眼镜护理液中和剂鉴定试验方法,评价其合理性。方法采用悬液定量杀菌试验程序,对含过氧化氢与双胍类成分的隐形眼镜护理液中和剂鉴定试验结果作出评价。结果此类隐形眼镜护理液对以金黄色葡萄球菌为代表的细菌杀菌力相对较强,试验中的第1组与第2组之间的差异比较明显;对白色念珠菌杀菌力较弱,第1组与第2组之间的差异不明显,影响结果判定。两种试验菌第3、第4和第5组间菌数误差率均不超过15%。结论杀菌力较弱的双胍类护理液中和剂鉴定试验中指标菌为白色念珠菌时,应适当调整对第1、2组判定标准或允许两组菌数接近。

Objective To study the verification test method for neutralizer of contact lens care solution and evaluate its reasonableness. Method Suspension quantitative germicidal test was used to evaluate the result of verification test for neu- tralizer of contact lens care solution containing hydrogen peroxide and biguanides. Results This kind of contact lens care solution had relatively strong germicidal effect on bacteria with Staphylococcus aureus as the representative and the differ- ence between first group and second group in the test was obvious. The killing effect on Candida albicans was weak and the difference between first group and second group was not obvious, thus influencing the judgement of results. The error rates of counts of two test bacteria between third, fourth and fifth groups did not exceed 15%. Conclusion When Candida albicans was used as indicator in verification test for neutralizer of contact lens care solution containing mainly biguanides which have weak germicidal effect, the judging criteria for first and second groups should be adjusted or approximation of bacteria counts of the two groups is allowed.