57例COPD氧疗中可允许高碳酸血症的初步分析

INVESTIGATION TO THE PERMISSIVE HYPERRAPNIA WITH 57 CASES COPD OXYGEN OPERATION

目的：评价低流量氧疗对慢性阻塞性肺疾病病人急性期血气及通气功能的影响，从而对新近有学者提出的氧疗过程中允许性高碳酸血症见解进行尝试性分析。方法：采用回顾性分析方法，对我院５７例慢性阻塞性肺疾病急性期病人住院期间，前三日氧疗中血液气体分析中氧分压与二氧化碳分压的动态变化，及临床症状改善的关系进行了分析。结果：ＣＯＰＤ氧疗过程初期大部分患者存在有限度的二氧化碳分压升高，发生率为８０．２８％。结论：对于ＣＯＰＤ患者缺氧是致命的关键，在氧疗中允许一定程度的二氧化碳分压升高，其升高幅度＜２ｋＰａ（１５ｍｍＨｇ）时继续氧疗是安全的。

Objective: To evaluate the effect of treatment with low airflow oxygen to the gases in blood and vetilation function at acute patients with chronis obstructive pulmonary disease.The resent idea of using permissive hyperrapnia during the oxygen treatment was analysed.Methods:57 cases COPD patients PaO_2 and PaCO_2 changing during the first 3 days of oxygen operation were analysed.Results:In the first period,an increase of PaCO_2 was shown with most patients.The raise percentage is 80.28%.Conclusions:Anaxemia is fatal to the patients.It is safe to use oxygen operation continuesly with the expantancy range within 2kPa (15mmHg).