摘要
目的探讨感染丙型肝炎(HCV)与血液透析(HD)、输血的关系及临床指导意义。方法用ELISA和PCR法检测128例血液透析患者血清中抗HCV和HCV-RNA。结果HD丙型肝炎病毒感染明显高于对照组(P<0.01),HD输血组明显高于非输血组(P<0.01),而HD输血组与非输血组,乙型肝炎病毒感染差异无显著性(P>0.05)。结论血液透析(HD)易感染丙型肝炎病毒,输血是引起HD患者丙型肝炎病毒感染的最主要原因。接受异体输血的次数和输血量越多,感染的机率越大,阳性检出率则越高。
Objective To investigate the relationship between HCV infection and blood transfusion of maintenance hemodialysis patients.Methods The HCV antibody and HCV-RNA of 128 hemodialysis patients were deteeted by ELISA and PCR method. Results The HCV infection rate of hemodialysis patients was higher than control group （ P 〈 0.01 ）. And the infection rate of hemodialysis patients received blood transfusion was higher than the patients who had not received （ P 〈 0.01 ）. But there was no significant difference in HBV infection. Conclusion Hemodialysis patients are susceptible to HCV infection, blood transfusion is the main cause of infection, and the infection rate is positively related to the quantity and times of transfusion.
出处
《中国实验诊断学》
北大核心
2009年第9期1202-1204,共3页
Chinese Journal of Laboratory Diagnosis
关键词
血液透析
丙型肝炎
输血
hemodialysis
hepatitis C
blood transfusion
