胸腹腔积液CRP与生化指标测定的临床意义

The value of the measurement of C-reactive protein and biochemistry marker of hydrothoratic and ascitic fluid

目的探讨胸腹腔积C反应蛋白(CRP)、生化指标在鉴定胸腹腔积液性质中的临床意义及其相关性。方法收集63例胸腹腔积液,采用金标法做CRP定量检测与采用BECKMAN COUL LX20全自动生化仪做生化指标定量检测,结合临床诊断进行统计学分析处理。结果渗出性胸腹腔积液自动生化仪中CRP、乳酸脱氢酶(LDH)、总蛋白(TP)、腺苷脱胺酶(ADA)水平明显高于漏出液(P<0.01),葡萄糖(GLU)水平低于漏出液(P<0.05),差异有统计学意义。CRP与LDH、GLU、TP、ADA有一定相关性。结论CRP、LDH、GLU、TP、ADA浓度测定对鉴别胸腹水性质有一定临床价值。

Objective To investigate the value and the correlation of the measurement of C-reactive protein and biochemistry marker in the differentiation of the nature of hydrothora tic and ascitic fluid. Methods C-reactive protein and biochemistry of hydrothoratic and ascitie fluid were determined in 63 patients, the data were analyzed union clinical diagnosis. Results According to the Criteria used 38 patients were included in Exudate and 25 patients in Transudate. The levels of the CRP, the LDH, the TP, and the ADA were significantly higher in exudate group than in transudate group （ P 〈 0.01 ）. The levels of the GLU were lower in exudate group than in transudate group （ P 〈 0.05）. There was a correlation between CRP and LDH, GLU, TP, ADA. Conclusion The measurement of CRP, LDH, GLU, TP and ADA is belpful to identify the nature of bydrothoralie and ascilic fired in the diagnosis.