闭合性颅脑外伤患者事件相关电位的检测

DETECTION OF EVENT-RELATED POTENTIALS IN PATIENTS WITH CLOSURE CRANIOCEREBRAL TRAUMA

对64例闭合性颅脑外伤患者分别采用视觉（图像）、听觉刺激诱发事件相关电位（ERP），其P3波潜伏期较正常对照组明显延长（P＜0．001）。ERP中P3波潜伏期、波幅与患者的病情严重程度密切相关（P＜0．001）。其中31例患者进行了ERP复测。两次P3波潜伏期有极显著的差异（P＜0．001）。结果提示，ERP可作为观察颅脑外伤患者脑认知功能损害程度及其恢复程度的一种客观指标。

Event-related potentials (ERPs), which were evoked by visud (image) and auditorystimuli, were recorded in 61 patients with closure cranio cerebral trauma. The P3 latency of which was significantly prolonged compared with the matched control (P<0. 001 ). The P3 latency and amplitude in ERPwere closely related to the severity of the disease. ERPs were recorded in 31 of the patients repetitively andmarked difference was found between the former and the latter results (P<0. 001 ). It suggests that ERPcan be taken as an objective index on observation of the extent of the defeciency and recurrence of the braincognition function in patients with colsure craniocerebral trauma.