活血破瘀等中药对^(125)I标记的大肠杆菌腹腔吸收的影响

Research on Effects of 125I EColi Absorption in Rat Peritoneum Induced by Huoxue Poyu Herbs

目的：观察活血破瘀药物对腹腔内致病菌吸收的影响。方法：应用大鼠急性化脓性腹膜炎模型，用活血破瘀及清热解毒等中药进行治疗，并观察中药对１２５Ｉ标记的大肠杆菌腹腔吸收的影响。结果：活血破瘀中药能增加生理情况下腹腔对细菌的吸收能力（Ｐ＜０．０５）及腹膜炎情况下的吸收能力（Ｐ＜０．０１）。活血破瘀与清热解毒中药联合应用亦能增加生理情况下腹腔对细菌的吸收能力（Ｐ＜０．０５）及腹膜炎情况下的吸收能力（Ｐ＜０．０５）。

bjective:To investigate the influence on pathogenic bacteria absorption in the peritoneum induced by herbsMethods:Using pathogenic Ecoli labelled with isotope 125I to observe the absorption of the pathgoens in the peritoneum of rat model of acute infective peritonitis and observe the effects of Huoxue Poyu herbs on the absorptionsResults:The ability of reabsorption of Ecoli in the peritoneum by Huoxue Poyu Herbs were more increased than in the normal physiologic conditions(P<0.05) and in acute peritonitis(P<0.01)The ability of reabsorption of Ecoli in the peritoneum could also be increaseed by the combination of Qingre Jiedu with Hoxue Poyu herbs through gastric ingestion(P<0.05)Conclusion:The ability of bacteria reabsorption in peritoneum can be enhanced by Huoxue Poyu herbs in the early stage of acute peritonitis