奥美拉唑注射液治疗消化性溃疡上消化道出血62例疗效分析

Omeprazole Injection in Treatment of Peptic Ulcer and Upper Gastrointestinal Hemorrhage :Efficacy Analysis of 62 Cases

目的探讨奥美拉唑治疗上消化道消化性溃疡出血的临床疗效。方法使用注射用奥美拉唑治疗消化性溃疡出血62例为治疗组,过去使用西咪替丁针剂治疗相似病人58例为对照组。结果治疗组显效、有效、无效率分别为24.19%、72.58%、3.23%,对照组分别为13.79%、60.34%、25.86%。2组比较,差异有统计学意义(χ2=13.20,P<0.01)。结论2种药物均适用于消化性溃疡出血的病人,但注射用奥美拉唑疗效更佳。

[ Objective] To investigate the clinical efficacy of Omeprazole in treatment of peptic ulcer hemorrhage. [ Methods ] 62 cases with peptic ulcer hemorrhage with omeprazole injection treatment were selected as treatment group, the similar 58 cases who had received cimetidine injection treatment as control group. [Results]Markedly effective, effective, ineffective of 24.19% , 72.58% , 3.23% respectively in treatment group, compared that in the control group （ 13.79%, 60.34% , 25.86% ） , the differences were significant （ X^2 = 13.20, P 〈 0.01 ）. [ Conclusion ] Either of the 2 drugs is applicable to patients with peptic ulcer hemorrhage, but a better effect of omeprazole injection.