心肺功能运动试验和静态肺功能对评判COPD患者病情轻重程度的比较

Comparison of Cardiopulmonary Exercise Test and Resting Pulmonary Test for Identifying the State of COPD Patients

【目的】比较心肺功能运动试验（CPET）和静态肺功能（PFT）对评判慢性阻塞性肺疾病（COPD）患者病情轻重的相关性。【方法】98名处于稳定期的COPD患者分别进行PFT和CPET检查；以PFT中FEV，％（占预计值％）和CPET中最大公斤摄氧量（VO2max／kg）两种不同方法判断COPD患者病情轻重并作相关性分析，同时以VO2max／kg判断COPD病情重于以FEV1％判断的患者与余下的患者作比较。【结果】两者方法判断COPD患者病情轻重无相关关系；以VO2max／kg判断病情较重的患者其年龄、FEV1％、V02max／kg、无氧阈占最大摄氧量比值（AT／VO2max）、最大呼吸储备（BRmax）与其他患者比较差异均有显著性。【结论】①CPET和PFT判断COPD患者病情并无相关性，但CPET反映病情更全面。②CPET有助于发现COPD患者潜在的心功能问题。

[Objective] To compare the correlation between cardiopulmonary exercise tests （CPET） and the rest- ing pulmonary test in the classification of chronic obstructive pulmonary disease（COPD） patients according the severity. [Methods] A total of 98 COPD patients in the stable stage were given CPET and PFT. All the patients were classified according to the FEV1% and the maximal oxygen uptake per kilogram of body weight （VO2max/kg） respec- tively and the correlation between the two classifications were studied. In the patients more impaired according to the VO2max/kg, some parameters were compared with the remaining patients. [Results] There was no significant correla- tion between the two classification methods. There was significant difference in age, FEV1 %, VO2max/kg, anaerobic threshold （AT） /VOz maximal breathing reserve （BRmax） between the patients more impaired according to VO2max/kg and the remaining patients. [Conclusion]There is no significant correlation between the classification ac- cording to CPET and the classification according to PFT, although CPET is believed to be more accurate. CPET is helpful to find the potential heart failure in COPD patients.