局部支气管灌洗液癌胚抗原浓度测定对周围型肺癌的诊断价值

Peripheral Lung Cancer Evaluated by Concentration of Carcinoma Embryonic Antigen (CEA) in Local Bronchial Lavagexx

目的探讨测定癌灶局部支气管洗出液癌胚抗原(CEA)浓度能否作为诊断周围型肺癌的辅助指标.方法统计20例经手术切除.经病理诊断为周围型肺癌,术前病灶局部支气管灌洗液CEA浓度与20例非肺癌者下叶支气管灌洗液CEA浓度对比.结果周围型肺癌支气管灌洗回收液平均CEA浓度为58.6±2.4μg/L,非肺癌灌洗液平均CEA浓度为12.3±8.7μg/L.两者对比有显著性差异(P<0,01).结论局部支气管灌洗液CEA浓度测定对周围型肺癌有一定的诊断价值,可弥补纤支镜活检及刷检之不足,对尽早诊断周围诊断周围型肺癌,争取早期手术治疗有指导意义.

Objective:To study the concentration of carcinoma embryonic antigen(CEA) in local bronchial lavage in diagnosing peripheral lung cancer.Method:CEA level of bronchial lavage in 20 patients with peripheral lung cancer confirmed by operation and biopsy and 20 subjects without lung cancer was compared. Results: Average CEA concentrations were 58.6±21.4μg/L in patients with peripheral lung cancer and 12.3±8.7 μg/L in subjects without lung cancer. Significant difference was found between these two groups(P<0.01).Conclusion:CEA concentration in local bronchial lavage can be used as supplements in diagnosing peripheral lung cancer in some extend.