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氯吡格雷联合辛伐他汀治疗不稳定心绞痛的效果评价

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摘要 目的:评价在常规治疗的基础上联合氯吡格雷和辛伐他汀治疗不稳定心绞痛(UA)患者的效果。方法:100例UA患者随机分为对照组和观察组,对照组采用硝酸酯类、β-受体阻滞剂、钙拮抗剂、阿司匹林、低分子肝素等常规治疗,观察组在常规治疗的基础上联合使用氯吡格雷和辛伐他汀。疗程结束后对两组患者疗效比较。结果:观察组临床总有效率为92.00%,高于对照组的临床总有效率72.00%,具有显著差异(χ2=6.7751,P<0.01)。观察组:未见明显的不良反应;对照组:2例发生轻微出血,主要是皮肤局部的淤点;两组均无因严重不良反应而中断治疗的病例。结论:观察组在常规治疗的基础上联合氯吡格雷和辛伐他汀治疗UA患者疗效佳,而且具有良好的安全性及耐受性,建议临床进一步推广应用。
作者 汪一琴
出处 《亚太传统医药》 2009年第9期90-91,共2页 Asia-Pacific Traditional Medicine
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