老年冠心病患者血清内源性洋地黄样因子浓度变化的初步观察

Changes of Serum Endogenous Digitalis-Like Factor of the Elderly with Coronary Heart Disease

本文用放射免疫方法测定20例老年冠心病患者和15例正常老年人血清内源性洋地黄样因子(EDF)浓度。结果发现:AMI患者血清EDF浓度明显高于正常老年人和稳定型心绞痛患者(P均<0.01),合并心房纤(?)者血清EDF浓度明显低于窦性节律者(P<0.01),血清EDF浓度与血钠浓度呈明显正相关(r=0.4783,P<0.05)。

Concentrations of serum endogenous digitalis-llke factor(EDF)were determined by radioimmunoassay in 20 aged patients with coronary heart disease and 15 normal cases. The results showed that the concentrations of serum EDF in patients with AMI were significantly higher than those of the normal and patients with stable angina pectoris(P<0.01). The concentrations of serum EDF in patients with atrial fibrillation were also significantly lower than those of sinus rhythm(P<0.01). The coneentrations of serum EDF and Na^+ were significantly correlated(r=0.4763, P<0.05).