miRNAs在红系造血过程中的作用

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摘要 microRNAs（miRNAs）是一类普遍存在的长度约为19—25个核苷酸的小RNA，通过与靶基因mRNA31端非编码区结合在转录后水平抑制靶基因的表达。从而参与调控个体发育、细胞凋亡、增殖及分化等生命活动。近来研究发现miRNA可以和其他红系转录因子相互作用，调节红细胞的生成。

作者邹成林(综述) 李占全(审校) 崔森(审校) 冀林华(审校)

机构地区青海大学医学院青海大学附属医院血液科

出处《国际输血及血液学杂志》 CAS 2009年第5期425-427,共3页 International Journal of Blood Transfusion and Hematology

基金青海省科技厅资助项目,项目编号：2008-Z602

关键词微小RNA 转录因子红细胞生成

参考文献21

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国际输血及血液学杂志

2009年第5期

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