Matrix与裸圈栓塞颅内动脉瘤的疗效比较

Embolization of intracranial aneurysms with Matrix coils versus Bare coils

目的比较Matrix与裸圈栓塞治疗颅内动脉瘤的疗效。方法采用单纯弹簧圈栓塞囊性动脉瘤173个,其中裸圈栓塞92个,Matrix栓塞81个。回顾性分析两种弹簧圈栓塞动脉瘤后即刻造影结果、栓塞密度、造影随访结果等。结果Matrix组与裸圈组的完全栓塞率分别为56.8%和82.6%(P=0.001),平均栓塞密度分别为(22.0±8.8)%和(25.4±9.1)%(P=0.015)。随访1～32个月,平均9.3个月;随访结束时,动脉瘤完全栓塞率分别为54.1%和79.4%(P=0.024),而再通率分别为21.6%和17.6%(P=0.674)。结论裸圈栓塞治疗颅内动脉瘤的短期疗效优于Matrix,但长期疗效仍需进一步观察研究。

Objective To evaluate the efficiency of embolization of intracranial aneurysms with Matrix versus Bare coil. Methods One hundred and seventy three aneurysms were embolized with coils, 81 out of them with Matrix coils and 92 with Bare coils. The outcomes of immediate angiography, packing attenuation and angiographic follow-up were retrospectively analyzed. Results Complete embolization rate and mean packing attenuation were 56.8% and 82.6% （P= 0.001）, and 22.0＋8.8% and 25.4±9.1% （P = 0.0146） in the Matrix coil group and Bare coil group respectively. The follow-up period ranged from 1 month to 32 months, with a mean of 9.3 months. According to the results of angiographic follow-up, the complete obliteration rate was 54.1% and 79.4% （P = 0.024） in the Matrix coil group and Bare coil group, while recanalization rate of the aneurysms was 21.6% and 17.6% （P = 0.674）, respectively. Conclusion The short-term efficacy of endovascular embolization with Bare coil is superior to Matrix coil, while the long-term efficacy should be further investigated.