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曲安奈德在前段玻璃体切割术中的应用

The clinical effect oftriamcinolone acetonide applicated in the anterior vitrectomy
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摘要 目的观察应用曲安奈德在前段玻璃体切割术中的临床效果。方法在43例47只眼行前段玻璃体切割手术中,利用曲安奈德附着于玻璃体的性质,单次或多次向前房内注射曲安奈德,实施了准确的前段玻璃体切割术,术后观察视力、角膜情况、前房内炎症反应、眼压变化、黄斑水肿情况等。结果瞌安奈德能清晰显示透明的玻璃体,安全准确地切除目标玻璃体,同时术后炎症反应明显减轻。术后最终随访视力稳定提高,无其他严重并发症发生。结论在前段玻璃体切割术中使用曲安奈德,可以提高手术的安全性和时效,抑制术后炎症反应,减少近期并发症,视力预后较好。 Objective To explore the clinical effect oftriamcinolone acetonide applicated in the anterior vitrectomy.Methods A clinical retrospective study of 43 patients including 47 eyes who underwent precise anterior vitrectomy with the application of triamcinolone acetonide by one time or several times was conducted.After surgeries, the visual acuity, the cornea opacity, the inflammatory reactions in the anterior chamber, the changes of intraocular pressure and the edema of the macular were recorded.Results Triamcinolone acetonide stained the anterior vitreous body so well that the tissue and the boarder were discovered clearly and it was easier to cut away thevitreous body.At the same time, it facilitated to ease the inflammation and the visual acuity was improved greatly without other severe adverse effect.Conclusions The application of triamcinolone acetonide has the superiority in boosting the safety of the anterior vitrectomy, reducing the wasted time, inhibiting the inflammation, decreasing the incidence of complication and improving the visual acuity.
出处 《中国实用眼科杂志》 CSCD 北大核心 2009年第9期1004-1006,共3页 Chinese Journal of Practical Ophthalmology
关键词 前段玻璃体切割术 曲安奈德 Anterior vitrectomy Triamcinolone acetonide
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参考文献10

  • 1Nishimura A,Kobayashi A, Segawa Y,et al .Isolatingt riamcinolone acetonide particles for intravitreal use with a porous membrane filter. Retina, 2003,23 : 777-779.
  • 2谢立信,姚瞻,黄钰森,应良.超声乳化白内障吸除术后角膜内皮细胞损伤和修复的研究[J].中华眼科杂志,2004,40(2):90-93. 被引量:301
  • 3Hogan M J, Kimura S J, Thygeson P.Signs and symptoms of uveitis.I.Anterior uveitis.AmJ Ophthalmol, 1959,47:155-170.
  • 4江明性.药理学.4版.北京:人民卫生出版社,1996:354.
  • 5Sakamoto T, Miyazaki M, Hisatomi T, et al .Triamcinolone - assisted parsplana vitrectomy improves the surgical procedures and decreases the postoperative blood-ocular barrier breakdown .Graefes Arch Clin Exp Ophthalmol, 2002,240: 423-429.
  • 6Hida T,Chandler D, Arena JE,et al..Experimental and clinical observations of the intraocular toxicity of commercial corticosteroid preparations. Am J Ophthalmol, 1986,101 : 190-195.
  • 7Oh JY, Wee WR, Lee JH, et al.Short-term effect of intracameral triamcinolone acetonide on corneal endothelium using the rabbit mode.Eye, 2007,21:812-818.
  • 8张凤妍,杜珊珊.并发性白内障术中前房注射曲安奈德的临床研究[J].中国实用眼科杂志,2007,25(5):492-494. 被引量:21
  • 9相杭,陈悦,黄少华.先天性白内障术中玻璃体内注射曲安奈德抑制术后前房渗出的临床研究[J].眼外伤职业眼病杂志,2008,30(5):337-340. 被引量:1
  • 10Moshfeghi DM, Kaiser PK, Scott IU, et al .Acute endophthalmitis following intravitreal triamcinolone acetonide injection.Am J Ophthalmol, 2003,136:791-796.

二级参考文献23

  • 1张凤妍,陈陆霞.地塞米松缓释剂在并发性白内障术中前房植入[J].眼外伤职业眼病杂志,2004,26(8):529-531. 被引量:7
  • 2刘武,王景昭.玻璃体内注射曲安奈德的问题与并发症[J].中华眼底病杂志,2005,21(4):267-270. 被引量:39
  • 3张凤妍,杜珊珊.并发性白内障术中前房注射曲安奈德的临床研究[J].中国实用眼科杂志,2007,25(5):492-494. 被引量:21
  • 4Jin LM, Carsten HM, Arnd HM, et al. Intraoperative intraocular triamcinolone injection prophylaxis for post-cataract surgery fibrin formation in uveitis associated with juvenile idiopathic arthritis. J Cataract Refractive Surgery,2006,32(9): 1535-1539
  • 5Gillies M, Simpson JM, Billson FA ,et al. Safety of an intravitreal injection of triamcinolone: results from a randomized clinical trial. Arch Ophthalmol,2004,122(3): 336-340
  • 6Enaida H, Sakamoto T, Ueno A,et al. Submacular deposition of triamcinolone acetonide after triamcinolone-assisted vitrectomy. Am J Ophthalmol,2003,135(2): 243-246
  • 7Tan DH, Chee SP, Lim L,et al.Randomized clinical trial of surodex steroid drug delivery system for cataract surgery.Ophthahnology, 2001,108(12):2172-2181
  • 8Xie L, Sun J, Yao Z. Heparin drug delivery system for prevention of posterior capsular opacification in rabbit eyes. Graefes Arch Clin Exp Ophthalmol,2003,241 (4):309-313
  • 9P.M.Beer, S.J.Bakri and R.J.Singh et al. Intraocular concentration and pharmacokinetics of triamcinolone acetonide after a single intravitreal injection. Ophthalmology,2003,110:681-686
  • 10Hosal BM, Biglan AW. Risk factors for secondary membrane formation after removal of pediatric cataract [ J]. Cataract Refract SurE. 2002,28 ( 2 ) : 302-309.

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