期刊文献+

3,5-二羟基戊苯(Olivetol)的合成进展 被引量:2

Research Progress on Synthesis of 1-n-pentyl-3,5-dihydroxybenzene (Olivetol)
下载PDF
导出
摘要 3,5-二羟基戊苯是有生理活性的重要化合物,也能用来合成大麻素,用于止痛、镇静、抗炎、助消化和抗高血压等,显示出广阔的应用前景,综述了其合成方法,比较了优缺点。 1 -n -pentyl -3, 5 -dihydroxybenzene was an important physiological activity compound and also could be used to synthesize cannabinoids for pain, sedation, anti - inflammatory, aid - digestion and anti - high blood pressure. It had broad application prospects. This review described synthetic methods of 1 - n - pentyl - 3, 5 - dihydroxybenzene and compares both virtue and shortcoming.
出处 《广州化工》 CAS 2009年第6期25-29,共5页 GuangZhou Chemical Industry
关键词 病毒抑制剂 3 5-二羟基戊苯 合成 Virus inhibitor 1 - n - pentyl - 3, 5 - dihydroxybenzene synthesis
  • 相关文献

参考文献19

  • 1Brown, G. D. Two New Compounds from Artemisia annua [ J J, J. Nat. Prod. 1992, 55 : 1756 - 1760.
  • 2Appendino, G. , Gibbons, S. , Giana, A. , Pagani, A. , Grassi, G. , Stavri, M. Smith, E. , Rahman. M. M. Antibacterial Cannabinoids from Cannabissativa: A Structure Activity Study [ J], J. Nat. Prod. 2008, 71:1427 - 1430.
  • 3K-lawinek,M. ,Jaromin, A. ,Kombek, A. ,Zamowski, R. Alkylresorcinols in Selected Polish Rye and Wheat Cereals and Whole- Grain Cereal Products [J], J. Agric. Food Chem,2008, 56: 7236. -7242.
  • 4LytoUis, W. ,Scannell,K T. ,An,H. ,Murty,V. S. ,Reddy,K. S. ,Barr,J. R. , Hecht,S. M.5 - Alkylresorcinols from Hakea trifurcata,that cleave DNA [J] ,J. Am. Chem. Soc,1995,117:12683 -12690.
  • 5Travis, C. A. Alkylated resorcinol derivatives for the treatment of immune diseases [ P], US6274635,2001 - 08 - 14.
  • 6Teske, J. A., Deiters, A. A Cyelotrimerization Route to Cannabinoids [J] ,Org. Lett,2008,10:2195 -2198.
  • 7Trost, B. M. , Dogra, K. Synthesis of ( - ) - □ - trans - Tetrahydrocannabinol : Stereocontrol via Mo - Catalyzed Asymmetric Allylic Alkylation Reaction [ J ], Org. Lett,2007,9 : 861 - 863.
  • 8Mannor, B. S. , An improved synthesis of 5 - alkylresorcinols [ J ], J. Org. Chem. , 1972,37 : 2901 - 2904.
  • 9Focella, A. ,Teitel, S. , Bressi, A. A simple and practical synthesis of olivetol [J] ,J- Org. Chem. ,1977,42: 3456 -3457.
  • 10Jaxa - Chamiec, A. A. , Sammes, P. G. A new route to 5 - substituted resorcinols and related systems,J. Chem. Soc., Perkin Trans. I , 1980: 170 - 175.

二级参考文献11

  • 1徐宇伦,张龙,金鑫,宋义新.HIV病毒抑制剂中间体3,5-二羟基戊苯(olivetol)的新合成方法[J].精细化工,2006,23(4):382-385. 被引量:7
  • 2Travis.Alkylated resorcinol derivatives for the treatment of immunedisease[P].US:6 274 635,2001-08-14.
  • 3E A Formukong,A T Evans,F J Evans.Analgesic and antiinflammatory activity of constituents of cannabis satival[J].Inflammation,1988,12.
  • 4Gosteli.Process for the preparation of 5-substituted resorcinols and related intermediates[P].US:4 249 027,1981-02-03.
  • 5Gilman H,Schultze F.A test for Grignard reagent[J].J Am Chem Soc,1925,47:2002-2005.
  • 6Travis.Alkylated resorcinol derivatives for the treatment of immune diseases[P].USP 6 274 635,2001-08-14.
  • 7Alonso E,Ramon D J,Yus M.Simple synthesis of 5-substituted resorcinols:A revisited family of interesting bioactive molecules[J].Org Chem,1997,62(2):417-421.
  • 8Barr J R,Murty V S,Yamaguchi K,et al.5-Alkylresorcinols from Hakea amplexicaulis that cleave DNA[J].Chem Res Toxicol,1988,1(4):204-207.
  • 9Gosteli.Process for the preparation of 5-substituted rescorcinols and related intermediates[P].USP 4 249 027,1981-02-03.
  • 10Bharat B Aggarwal,Bryant G Darnay.Tumor necrosis factor receptor -I-associated protein kinase and methods of use therefore[P].USP 5 856 161,1999-01-05.

共引文献6

同被引文献26

引证文献2

二级引证文献11

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部