类风湿关节炎继发骨质疏松相关因素分析

Research on rheumatoid arthritis patients with secondary osteoporosis

目的:探索类风湿关节炎(RA)与骨质疏松症之间的关系。方法:测量RA患者骨密度(BMD),并对其结果进行统计分析。结果:RA骨质疏松与骨代谢的关系RA骨质疏松组中股骨颈BMD值与类风湿因子不相关(r=0.171,P>0.05),与病程、关节肿胀数、压痛数、血沉、C反应蛋白及x线分期的相关系数分别为r=-0.478、-0.669、0.452、-0.498、-0.641、-0.510,呈负相关。结论:类风湿关节炎与骨质疏松症之间相关性具有统计学意义,前者发展到后期常常导致骨质疏松。

Objective： To explore the relations between rheumatoid arthritis and osteoporosis. Methods： RA patients with measurement of bone mineral density （ BMD ） , and the results of statistical analysis. The results ： RA osteoporosis and bone metabolism in the relationship between the RA group osteoporesis and femoral neck BMD values not related to rheumatoid factor （ r = 0. 171, P 〉 0.05 ）, and course of disease, the number of joint swelling, tenderness to the number of erythrocyte sedimentation rate, C reactive protein and x - ray phases, respectively, for the correlation coefficient r = - 0. 478, - 0. 669, 0. 452, - 0. 498, - 0. 641, - 0.510, was a negative correlation. Conclusion： rheumatoid arthritis and osteoporosis statistical correlation between the significance and the former often leads to the development of osteoporosis.