浙江省丽水市学生乙肝病毒(HBV)感染状况分析

Analysis of hepatitis B virus infection in students in Lishui

目的：分析丽水市学生乙肝病毒（HBV）血清感染状况,为实施对健康人群乙肝疫苗免疫计划和乙肝的防治提供依据。方法：用酶联免疫吸附法（ELISA）进行HBsAg、HBsAb、HBeAg、HBeAb、HBcAb检测。结果：共检测学生血清16105份,HBsAg阳性率为4.92%;HBsAb阳性率为30.64%;病毒感染模式以＂大三阳＂和＂小三阳＂为主。其中1-7岁组HBsAg阳性率0.60%;8-13岁组HBsAg阳性率2.11%;14-19岁组HBsAg阳性率4.30%;≥20岁组HBsAg阳性率7.75%（性别χ^2=0.671,P〉0.05）。结论：乙肝病毒感染率随年龄段降低呈下降趋势,性别与感染不相关。HBsAb阳性率不高。建议加强健康教育预防乙肝传播,对学生进行乙肝疫苗的预防接种和强化免疫。

Objective： To provide evidence for the implementation of the plan of HB vaccine and the control of HBV infection by analyzing the Hepatitis B virus （HBV） infections in students in Lishui,ZheJiang Province. Methods： HBsAg, HBsAb, HBeAg, HBeAb and HBcAb were tested by Enzyme -linked Immunosorbent Assay （ELISA）. Results： 16105 students was tested with the positive rates of 4. 92% and 30. 64% for HBsAg and HBsAb,respectively. Most of these students come with the model of HBsAg （ ＋ ） ,HBeAg（ ＋ ） ,HBcAb（ ＋ ） or HBsAg（ ＋ ） ,HBeAb（ ＋ ） ,HBcAb（ ＋ ）. The positive rates of HBsAg are 0. 60% ,2. 11% , 4. 30% ,7. 75% among the 1 -7 years,8 -13 years, 14- 19 years and ≥20 years group, respectively（ sex χ^2 = 0. 671 ,P 〉 0. 05 ）. Conclusion：Hepatitis B virus （HBV） infection is related with age, the younger the lower, but not sex. The positive rate of HBsAb is low. It is suggested that advanced educations are needed for the prevention of the infections. All the students must be vaccinated and even reinforced.