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不同降调节方案对子宫内膜异位症患者IVF-ET妊娠结局的影响 被引量:11

Effect of Endometriosis with Different Down-regulation Protocol on Pregnancy Outcome of IVF-ET
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摘要 目的:探讨超长方案对子宫内膜异位症患者IVF-ET妊娠结局的影响。方法:回顾性分析79例(82个周期)子宫内膜异位症患者采用超长方案(42个周期)和常规长方案(40个周期)对IVF-ET妊娠结局的影响。结果:与常规长方案组相比超长方案组的获卵数(8.2vs10.7)、受精率(69.32%vs72.11%)、卵裂率(87.49%vs89.78%)无明显差异(P>0.05),但Gn总量(44.55支vs33.79支)、优质胚胎数(4.3vs5.8)、临床妊娠率(20.00%vs40.48%)、胚胎植入率(9.90%vs19.64%)等几项指标,超长方案组均显著增高(P<0.05)。结论:在IVF-ET超促排卵前,采用超长方案进行降调节能显著提高子宫内膜异位症患者IVF-ET的成功率。 Objective: To evaluate the effect of endometriosis with ultra-long-protocol on pregnancy outcome of IVF-ET. Methods: From January 2001 to June 2005, we retrospectively analyzed the pregnancy outcome of 82 IVF-ET cycles between and up-long down-regulation protocol (group A) general long down-regulation protocol (group B). Results: The number of oocytes (10.69 vs 8.18, the fertilization rate (72.11% vs 69.32%), the cleavage rate (89.78% vs 87.49%) were no significant difference between group A and group B (P〉0.05). But, the total number of gonadotropin (Gn) (33.79 vs 44.55), the number of good embryos (5.83 vs 4.25), the clinical pregnancy rate (40.48% vs 20.00%), the embryo implantation rate (19.64% vs 9.90%) of group A were significantly higher than group B, respectively (P〈0.05). Conclusion: The pregnancy outcome of IVF-ET cycles in endometriosis patients can be improved by using ultra-long down-regulation protocol.
出处 《生殖与避孕》 CAS CSCD 北大核心 2009年第9期613-616,共4页 Reproduction and Contraception
关键词 子宫内膜异位症(EMs) 体外受精-胚胎移植(IVF-ET) 临床妊娠率 胚胎植入率 endometriosis IVF-ET clinical pregnancy rate implantation rate
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参考文献19

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共引文献208

同被引文献123

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