不同注药速度对等比重罗哌卡因脊麻的影响

Influence of injection rate of isobaric ropivacaine on spinal anesthesia

目的探讨不同注药速度对等比重罗哌卡因脊麻在感觉阻滞和运动阻滞效果以及不良反应发生率的影响。方法择期行妇科手术的患者46例,使用1%罗哌卡因2.0mL(20mg)脊麻,注药速度分别为0.27mL/s(A组,n=23)和0.04mL/s(B组,n=23),观察两组感觉阻滞和运动阻滞效果以及术中低血压、恶心和呕吐等不良反应的发生情况,并进行组间比较。结果两组患者注药后30min内感觉阻滞平面达到T6的时间、达到最高感觉阻滞的平面及时间、达到最大运动阻滞的时间和不良反应的发生率差异均无统计学意义(P>0.05)。结论使用等比重罗哌卡因20mg行脊麻,0.27mL/s和0.04mL/s的注药速度在感觉阻滞和运动阻滞效果以及不良反应发生率上无显著差异。

Objective To investigate the influence of injection rate of isobaric ropivacaine on sensory block,motor block and adverse effects in patients undergoing gynecologic surgery.Methods Forty-six patients undergoing selective gynecologic surgery were randomly divided into group A and group B,with 23 patients in each group.2.0 mL of 1% ropivacaine（20 mg）was administered for spinal anesthesia.The injection rate of ropivacaine was 0.27 mL/s in group A and 0.04 mL/s in group B.The effects of sensory block and motor block were observed,adverse effects such as hypotension,nausea and vomiting were recorded,and data were compared between groups.Results Thirty minutes after ropivacaine injection,there was no significant difference in time to reach T6 in sensory block,level of maximum sensory block,time to reach maximum sensory block level,time to reach maximum motor block and prevalence of adverse effects between group A and group B（P〉0.05）.Conclusion There may be no significant difference in sensory block,motor block and prevalence of adverse effects between injection rates of 0.27 mL/s and 0.04 mL/s in spinal anesthesia with 20 mg isobaric ropivacaine.