严重烧伤早期处理对全身炎症反应综合症的影响

Effects of Early Treatment for Severe Burn Patients on Systemic Inflammatory Response Syndrome(SIRS)

【目的】研究严重烧伤早期处理对全身炎症反应综合症(SIRS)的影响作用。【方法】选取1999年1月到2008年12月在烧伤科住院的168例严重烧伤病人,回顾性分析早期正确的治疗方法对减少SIRS的作用。【结果】本组168例发生SIRS的人数为56例,发生率为38.1%;而SIRS患者中,有19例发生了多器官功能综合症(MODS),发生率为33.9%,其中9例死亡,死亡率为16.1%。【结论】对严重烧伤后患者早期进行有效急救,即平稳渡过休克期、及时防治感染、正确处理创面、免疫治疗及针对SIRS介质的治疗等,可以明显降低SIRS和MODS的发生率和死亡率。

[Objective] To study the effects of early treatment for severe burn patients on SIRS. [Methods] A total of 168 severe burn patients who were hospitalized in our hospital from 1999.1 to 2008.12 were studied retrospectively. [Results] The incidence of SIRS was 38.1% （56/168）; the incidence of MODS in 56 SIRS patients was 33.9% （19/56） and 9 cases （16.1%） were dead. [Conclusion] Prevention and cure of SIRS with early fully effective fluid resuscitation, adequate and effective application of antibiotics, specific immunotherapy and so on, can effectively block the occurrence and development of SIRS, reduce the incidence and mortality of MODS, thus greatly enhance clinical efficacy and improve the life quality of the patients.