消脂护肝胶囊对脂肪肝患者降脂作用的临床及实验研究

Clinical and Experimental Study on Fat Depression for Patients with Fatty Liver by Xiaozhi Hugan Capsule

消脂护肝胶囊由泽泻、山楂、生黄芪、草决明、赤芍、郁金、柴胡、金钱草组成。临床观察中，与东宝肝泰不完全随机对照，结果发现：两组Ｔ－ｃｈ、ＴＧ均降低，ＨＤＬ－ｃｈ均有升高，治疗组降Ｔ－ｃｈ、ＴＧ作用明显优于对照组，Ｐ＜０．０１。动物实验表明：本品大、小剂量均可使血清ＨＤＬ－ｃｈ水平升高，Ｔ－ｃｈ、ＴＧ明显降低，其降低幅度优于对照组，降肝匀浆甘油三酯水平与对照组无显著性差异。研究结果提示：高脂血症与全血粘度增高存在着正相关。该药在降脂的同时。

Abstract Xiaozhi Hugan capsule is composed of Alisol hawthorn fruit,fresh scutellaria root, cao Jumin,red peony root,curcuma root,bupleurum root,lysimachia.In the clinical observation,after the incomplete random comparison with the Dongbao Gantai group.The results showed that TC and TG of two groups decreased and HDL ch of both groups increased,the TC and TG reducing effecf of therapeutic grorp were remarkably higher than that of the controlled group ( P <0 01).The animal experiment showed that either larger or little dose of the medicine could increase the blood serum HDL C level,could remarkably decrease TC,and TG and the descending extent was higher than that of the controllcd group The descending hepatohomogenate triglyceride level was not significantly different from that of the controlled group The result suggests that the hyperlipemia has positive correlation with the whole blood viscosity, and the medicine has the effect of descending the whole blood viscosity,in addition to descend the blood fat.