盐酸丙哌维林治疗前列腺术后膀胱痉挛的疗效分析

The Curative Effect of Cystospasm Patients after Prostate Operation Treated by Propiverine hydrochloride

目的评价盐酸丙哌维林片治疗前列腺术后留置导尿致膀胱痉挛的疗效。方法对64例前列腺术后留置导尿出现膀胱痉挛的患者给于盐酸丙哌维林片治疗,20mg/次,1次/d,至拔除导尿管前24h。评价指标包括痉挛是否发生、发生频率、持续时间等。结果用药24h后,膀胱痉挛完全缓解16例(25%),部分缓解36例(56.3%),未缓解12例(18.8%)。72h后,膀胱痉挛完全缓解33例(51.6%),部分缓解24例(37.5%),未缓解7例(10.9%)。治疗过程中无严重不良反应发生。结论盐酸丙哌维林为治疗前列腺术后留置导尿致膀胱痉挛快速、有效、持久、安全的药物。

Objective To evaluate the efficacy of propiverine hydrochloride on cystospasm caused by the indwelling catheter after prostate operation. Methods 64 patients with cystospasm caused by the indwelling catheter after prostate operation received propiverine hydrochlofide （20mg daily）, until 24 hours before the removal of the catheter. Results After 24 hours of treatment, cystospasm was alleviated totally in 16 patients （25%）, partially in 36 patients （56.3%）, and unrelieved in 12 patients（18.8%）. After 72 hours of treatment, cystospasm was alleviated totally in 33 patients （51.6%）, partially in 24（37.5%）, and unrelieved in 7（10.9%）. No severe adverse events occurred during the treatment. Conclusion The propiverine hydrochloride therapy for patients with cystospasm caused by the indwelling catheter after prostate operations is rapid, effective, persistent and safe.