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适配子的临床应用前景展望

Outlook of prospects for clinical application of aptamer
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摘要 适配子(aptamer)是通过指数富集配体的系统进化(SELEX)技术得到的与靶分子特异结合的小分子核苷酸,它具备很多优点,在医疗界备受关注。适配子可以替代传统抗体,并显示出更多的优越性。与目前应用于临床研究或制药的几种核苷酸比较,适配子的应用前景更乐观。 Aptamer is small molecule nucleotide obtained by systematic evolution of ligands by exponential enrichment(SELEX) technology, it can combine with target specifically. It has many advantages and has drawn greater attention in the medical riel& It can be an alternative to traditional antibodies and shows more superiority. Compared with other nucleotides uesd in clinical research or pharmacy at present, the application prospect of aptamer is more optimistic.
出处 《国际肿瘤学杂志》 CAS 2009年第9期679-681,共3页 Journal of International Oncology
关键词 适配子 核苷酸类 抗体 Aptamer Nucleotides Antibodies
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