摘要
目的:探讨江苏省结核病治疗依从性现状并分析其影响因素,为制订有针对性的干预措施提供科学依据。方法:随机抽取13个样本点,各样本点连续性收集2006年1月1日起登记报告的60例涂阳肺结核患者为研究对象,由经过培训的调查员采用结构式调查表进行问卷调查,并分析依从性现状及不规则治疗的影响因素。结果:670名结核病患者在治疗过程中有82人存在不规则服药现象,不规则治疗比例12.2%。不规则服药的主要原因是药物不良反应(37.8%)。患者的文化程度及服药方式是影响依从性的主要影响因素。结论:依从性是当前结核病控制工作的一个重要课题,应当关注重点人群,采取以规范督导为主的综合干预措施降低不规则治疗的风险,提高治愈率。
Objective：To describe the current status of patients＇ adherence to anti-tuberculosis medications and identify risk factors associated with treatment interruption in Jiangsu,aud provide evidences to explore intervention measures. Methods： 13 counties （districts） were randomly sampled as study sites. On each site,60 sputum smear-positive tuberculosis patients registered since January 1,2006 were selected as study subjects and interviewed by a structured questionnaire. Risk factors associated with non-adherence were analyzed. Results：82 of 670 enrolled pulmonary tuberculosis patients interrupted treatment, accounting for 12.2%. Drug side effect was the most important factor causing patients non-adherence （37.8%）. Patients＇ education and the way of taking medicine were the main influence factors affecting patients＇ adherence. Conclusion：More importance should be attached to treatment adherence under the current DOTS strategy. Synthetic measures taken to focus groups can reduce the risk for interruption and increase cure rate.
出处
《南京医科大学学报（自然科学版）》
CAS
CSCD
北大核心
2009年第10期1384-1388,共5页
Journal of Nanjing Medical University(Natural Sciences)
基金
中国全球基金结核病项目实施性研究(TB07-014)
关键词
肺结核
治疗
依从性
危险因素
pulmonary tuberculosis
treatment
adherence
risk factor
