缺碘地区母婴分娩状态性别体重对新生儿TSH水平的影响

Effects of mothers and neonates with different physiologic conditions on neonatal TSH level distributions

为探讨缺碘地区母婴不同分娩状态及各种生理因素对新生儿促甲状腺激素（ＴＳＨ）水平分布的影响，应用免疫放射分析（ＩＲＭＡ）测定了１５７９名新生儿脐带血ＴＳＨ水平。结果发现，ＴＳＨ值＞５ｍＵ／Ｌ者所占百分数，城镇新生儿的为１９．７％，农村的为２５．９％（Ｐ＜０．０５），女婴的为２８．１％，男婴的为２１．４％（Ｐ＜０．０１），难产的为３１．８％，足月顺产的为２３．３％（Ｐ＜０．０５）；ＴＳＨ值≥２０ｍＵ／Ｌ者所占百分数，早产的为５．３％，足月顺产的为０．４％（Ｐ＜０．０１），重度缺氧的为１２．５％，正常的为０．４％（Ｐ＜０．０１）。提示不同地区、新生儿性别、母亲分娩状态及新生儿缺氧程度对新生儿ＴＳＨ水平分布有一定影响。

To study the effects of mothers and neonates with different physiologic conditions on neonatal TSH level distributions,1579 neonatal umbilical cord whole blood TSH values were determined with immunoradiometric assay (IRMA).Results showed that the proprotins with neonatal TSH levels>5mU/L,were 19.7% in town and 25.9% at rural area (P<0.05),28.1% in female and 21.4% in male (P<0.05),respectively.It suggested that there were some effects on neonatal TSH level distributions among the different areas,sexes,labor conditions and the degree of lack oxygen.Thus,if neonatal TSH level distributions were applied to evaluate the iodine nutrition status of inhabitants,the factors described above should be taken into account properly.