补肾壮力方剂治疗男性慢性布氏菌病性功能低下的观察

Clinical and experimental studies on treating male sexual dysfunction of chronic brucellosis with the prescription of enriching kidney and strengthening energy

探讨治疗慢性布氏菌病（简称布病）性功能低下的及有效治疗方剂。通过测定６６例男性慢性布病患者及感染布氏菌后６个月豚鼠，血清中促黄体生成素（ＬＨ），促卵胞生成素（ＦＳＨ），雌二醇（Ｅ２）和睾酮（Ｔ）含量，并与正常组比较，观察其性腺系统功能状态；并用补肾壮力方剂治疗具有性腺系统功能减退病人和实验豚鼠，结果：病人及实验豚鼠，血清中ＬＨ、ＦＳＨ、Ｅ２和Ｔ含量出现明显变化，与正常组比较具有显著差异（Ｐ＜０．００５或Ｐ＜０．００１）。经用补肾壮力方剂治疗后，病人及实验豚鼠血清中Ｔ和Ｅ２含量增高，ＬＨ和ＦＳＨ含量下降，并且治疗后病人血清中４种激素含量与正常组比较均无显著差异（Ｐ＞０．０５），实验豚鼠治疗后与治疗前比较，Ｔ和Ｅ２含量有极显著差异（Ｐ＜０．０１），而ＬＨ和ＦＳＨ含量无显著差异（Ｐ＞０．０５）。病人治疗总有效率为８３．３３％。

To inquire into pathogenesis and effective treating prescription of sexual underfunction of chronic brucellosis,the functional state of sexual gland system of sixtysix cases of chronic brucellosis and experimental guinea pigs after infecting six months with brucella was observed by measuring content of luteinizing hormone (LH),folliclestimulating hormone (FSH),estradiol (E2) and lestosterone (T) in serum.The sexual underfunction patients and experimental guinea pigs (after infecting six months) were treated with enriching kidney and strengthening prescription.Treating effect was observed.Results showed the content of LH,FSH,E2 and T in serum of patients of chronic brucellosis and experimental guinea pigs changed obviously.As compared with the control group,the different was obvious (P<0.05 or P<0.01).After treating with enriching kidney and strengthening prescription,the content of T and E2 in serum of patients and experimental guinea pigs increased.The content of LH and FSH in serum of patients and experimental guinea pigs decreased.The total effective rates of treating patients were83.33%.indicated.