幽门螺杆菌感染与肝硬化的关系初探

Relationship between helicobacter pyloriinfection and cirrhosis of liver

用ＰＣＲ法、快速尿素酶试验及组织学染色检查法检测３５例肝硬化患者和３２例胃十二指肠病患者的Ｈｐ感染率，分别为７１．４％与６５．６％，两组比较差异无显著性（Ｐ＞０．０５）。有肝功能损害者，Ｈｐ感染率较肝功能正常者高，分别为７９．３％与３３．３％（Ｐ＜０．０５）。认为肝硬化患者Ｈｐ感染率较高。

Twenty-five (71.4%) of 35 cirrhotic patients were infected with Helicobacter pylor (Hp), compared with 21 (65.6%) of 32 patients with gastric or duodenal diseases (P>0.05). The Hp infection rate in patients with liver lesion was higher than that of patients without liver lesion (79.3% and 33.3%, respectively). Ten (83.3%) of 12 patients with hepatic encephalopathy were infected with Hp, compared with 15 (65.2%) of 23 patients without hepatic encephalopathy. The cirrhotic patients have a high Hp infection rate and those infected are at higher risk for hepatic encephalopathy.