外伤性白内障人工晶状体植入术后晶状体表面纤维蛋白膜形成

Proteinaceous membrane formation on lenses after traumatic cataractextraction and posterior chamber intraocular lens implantation

目的观察兔眼外伤性白内障后房型人工晶状体（ＰＣＩＯＬｓ）植入术后晶状体表面纤维蛋白膜的病变特征及规律。方法９只青紫蓝兔分为３组。术后１、７、１４ｄ摘除人工晶状体，作光镜和扫描电镜检查，采用ＳＡＳ软件包，对统计资料作方差分析。结果纤维蛋白厚膜术后ｄ１最明显，定位孔膜ｄ７最明显。薄膜ｄ１４最明显，差异有显著性。结论纤维蛋白膜形成的原因可能是人工晶状体刺激。

ObjectiveTo study the pathological changes and morphological features of proteinaceous membrane formation on intraocular lenses (IOLs) after traumatic cataract extracapsular extraction and posterior chamber intraocular lens (PC IOLs) implantation in rabbits.Methods9 adult pigmented rabbits were divided into 3 groups.IOLs were extracted on d 1,7 and 14 after IOLs implantation,and pathological changes were observed on IOLs with light microscope and scanning electron microscope.The data were analysed by rank sum test using SAS software.ResultsThick proteinaceous membranes on IOL reached their maximum on d 1 postoperation,and proteinaceous membranes in positioning holes on IOL reached their maximum on d 7 postoperation.Thin proteinaceous membranes on IOL were significantly higher on d 14 postoperation than those on d 1 postoperation.ConclusionIt is suggested that proteinaceous membrane formation on IOL have a close relationship with an irritation of IOL and breakdown of the blood aqueous barrier and immune response on the IOL surface.