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雷贝拉唑治疗十二指肠溃疡的临床观察 被引量:5

A clinical trial of Rabeprazole in the treatment of duodenal ulcer
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摘要 目的探讨雷贝拉唑治疗十二指肠溃疡的疗效。方法将77例十二指肠溃疡患者随机分为雷贝拉唑(10mg1次/d)治疗组和奥美拉唑(20mg1次/d)对照组。疗程4周。结果治疗组和对照组溃疡愈合率分别为95.2%和94.3%,总有效率均为100%,2组无显著性差异P(>0.05),但缓解疼痛时间治疗组显著优于对照组(P<0.01)。结论雷贝拉唑和奥美拉唑治疗十二指肠溃疡均有良好的疗效,而雷贝拉唑缓解腹痛作用较奥美拉唑更为明显,值得临床推广。 Objective To investigate the effect of rabeprazole on duodenum ulcer. Methods duodenum ulcer were divided into two groups: treat group by rabeprazole (10 mg one time/d ) and omeprazole (20 mg one time/d ). The course of treatment was 4 weeks. Results The 77 patients with control group by ratio of treatment group and comparison group was 95.2% & 94.3% respectively,and total validity was 100%.There was no significant difference (P〉0.05). However, easing pain time of the treatment group was shorter than the control group (P〈0.01). Conclusion Rabeprazole and omeprazole are effective on duodenum ulcer and rabeprazole is more effective on easing bellyache than omeprazole. It is woth to spread in clinic.
出处 《基层医学论坛》 2009年第26期771-772,共2页 The Medical Forum
关键词 十二指肠溃疡 雷贝拉 唑奥美拉唑 Duodenum ulcer Rabeprazole Omeprazole
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