角膜上皮下雾浊对角膜前表面形态的影响

The association of corneal surface shapes with “Haze”

目的探讨角膜上皮下雾浊（Ｈａｚｅ）对角膜前表面形态的影响。方法用ＴｏｍｅｙＴＭＳ２ＴＭ角膜地形图对不同程度Ｈａｚｅ眼进行检查，取得角膜规则指数（ＳＲＩ）、不对称指数（ＳＡＩ）和不规则散光指数（ＩＡＩ）统计值。用角膜Ｈａｚｅ０～４级的数值作Ｙ轴，分别与ＳＲＩ、ＳＡＩ和ＩＡＩ行直线回归分析。结果绝对等级角膜地形图显示高于１级的Ｈａｚｅ眼全角膜形态极不规则，０．５级Ｈａｚｅ以下角膜表面形态较为规整，各切削区带清晰可见。回归分析显示Ｈａｚｅ越重，对角膜前表面形态、规则性和对称性影响越大。结论超过１级Ｈａｚｅ眼对角膜前表面形态影响大，低于０．５级Ｈａｚｅ眼对角膜形态基本无影响，严重Ｈａｚｅ对角膜表面形态影响可能是导致ＰＲＫ术后最佳矫正视力下降的主要原因。

ObjectiveTo investigate the association of corneal surface shapes with “Haze” after photorefractive keratectomy(PRK).MethodsEyes with different “Haze” were examined by Tomey TMS 2 TM corneal topography,and corneal surface regularity index(SRI),surface asymmetry index(SAI) and irregular astigmatism index(IAI)were obtained.“Haze” was graded from 0 to 4 and was individually compared with SRI,SAI and IAI by linear regression analysis.ResultsCorneal surface shapes were irregular in eyes with “Haze” more than 1 scale,but there were no changes in less than 0.5 scale.Regression analysis showed that the more severe the “Haze”,the more changes in corneal surface shape,regularity and symmetry.ConclusionThe eyes with “Haze” more than 1 scale had a great influence on corneal surface shape.“Haze” less than 0.5 scale had little change in corneal surface shapes.The change of corneal surface shapes with severe “Haze” might be the main cause of the decreasion of best corrective visual acuity after PRK.