中医药治疗变应性鼻炎临床研究的思考与展望

Thinking and look forward to clinical study of allergic rhinitis by treatment of traditional Chinese medicine

变应性鼻炎(AR)是一种由IgE介导的,针对环境过敏原的鼻黏膜炎症反应性疾病,临床主要表现为鼻痒、喷嚏、流涕、鼻塞等。中医认为古病"鼻鼽"包括了AR。对比AR的临床表现特点和中医风邪致病特点及风病临床表现特点,可以看出AR应属中医风病范畴。近10年的中医临床研究文献显示,治疗AR处方中出现最多的药物是风药(每方均有)。文中针对近十年中医临床研究中存在的3方面问题,探讨今后研究应关注的5个问题,为中医治疗AR的临床与实验研究提供借鉴。

Allergic rhinitis （AR） is one kind of nose mucous membrane inflammation reactiveness disease , which is mediated by IgE for the environment sensitizin. The major clinical symptoms are ： nose itch , the sneeze , nasal discharge, nasal obstruction and so on. It is thought that the acient disease named ＂Bi Qiu＂ has included AR. By comparing the AR clinical manifestation characteristic with trditional Chinese medicine （TCM） ＂Feng/wind＂ induced disease characteristic and the ＂Feng/wind＂ disease clinical manifestation characteristic, we can know that AR should belong to the ＂ Feng/wind＂ disease category of TCM. It is shown that the ＂ Feng/ wind＂ medicine is the most windly appeared in AR treatment formulas of TCM clinical research data （ in each formular） in the past 10 years. To aim directly at three knids of problem in TCM clinical research, we discussed five problems which should pay close attention to the feature research, therefor to provide a mirror for AR clinical and experimental studies by TCM.