颅内肿瘤X刀治疗后短期影像学改变

A Short term Imaging Follow up for Brain Neoplasms Treated by X ray Knife

目的：探索颅脑肿瘤Ｘ刀治疗后短期生物学行为变化。材料与方法：收集Ｘ刀治疗后有完整影像学随访资料者４５例，随访时间２～１４个月，２５例行ＣＴ扫描，２０例同时有ＣＴ、ＭＲＩ资料。结果：Ｘ刀治疗后颅脑肿瘤发生以下影像学变化：（１）环样结构改变１５例（８０％为良性肿瘤）；（２）完全失强化或囊变（各２例）；（３）完全消失（６例），明显缩小（８例），轻度皱缩（８例），基本不变（１７例），继续增大（６例）；（４）瘤周水肿（２０例）；（５）放射性坏死（１例）。结论：颅内肿瘤Ｘ刀治疗后生物学行为变化存在较大差异。

Objective: To assess biological behavior changes in brain tumors following stereotactic LINAC radiosurgery (X ray knife).Materials and Methods:45 patients who had CT or both CT and MR examinations following treatment were involved in this study. The following period ranged from 2 to 14 months. 25 only had CT images and 20 had both CT and MR images.Results:The following changes had taken place after treatment: (1)Ring like structure (n=15, 80% are benign tumors); (2)Completely loss of contrast enhancement or cyst formation (n=2, respectively); (3)Complete disappear (n=6), marked decrease (n=8), slight decrease (n=8), unchanged (n=17) and others were increased in size (n=6); (4)Peritumour edema (n=20); (5)Radionecrosis (n=1).Conclusion: The behavior of cerebral tumors appear to be variable after the treatment with X ray knife, but all the changes can be demonstrated on CT and MR images.