摘要
目的:建立咳特灵胶囊中牡荆素的含量测定方法。方法:采用高效液相色谱法,色谱柱为迪马TC-C_(18)柱(250mm×4.6mm,5μm),流动相为乙腈-1%醋酸溶液(16:84),流速1.0ml·min^(-1),柱温25℃,检测波长为340nm。结果:牡荆素在0.087～0.866μg范围内呈良好的线性关系,r=0.999 6;平均回收率为101.07%,RSD为2.10%。结论:该方法简单、灵敏度南,可用于咳特灵胶囊中牡荆素的含量测定。
Objective： To establish an HPLC method for the determination of viterxin in Keteling capsule. Method： The TC-C18 col umn（250mm × 4.6mm,5μm）was used with acetonitrile -1% acetic acid solution（ 16： 84）as mobile phase. The flow rate was 1.0 ml·min^-1. The detecting wavelength was at 340 nm. Result： The linear range of viterxin was 0. 087 -0. 866μg,r =0.999 7. The average recovery was 101.07% ,and RSD was 2.10%. Conclusion： The method is simple ,rapid and accurate. It can be used to determine viterxin in Keteling capsule.
出处
《中国药师》
CAS
2009年第10期1402-1403,共2页
China Pharmacist
基金
贵州省中药现代化科技产业研究开发专项(编号:黔科合中药专字[2004]20号)
