婴幼儿颅脑损伤并发多器官功能障碍综合征56例分析

The analysis of 56 infant brain injury victims complicated with MODS

目的探讨婴幼儿颅脑损伤并发多器官功能障碍综合征(MODS)的发病机制,临床特点及早期治疗要点。方法总结分析2003-2007年我院收治三岁以下婴幼儿颅脑损伤特点及并发MODS患儿的临床资料。结果79例重型颅脑损伤的婴幼儿发生56例MODS(发生率70.88%),颅脑损伤后频繁抽搐,并发失血性休克是MODS的危险因素。结论婴幼儿颅脑损伤早期有效的呼吸循环的支持,控制抽搐是治疗的首要问题,明确需要治疗的颅内压(TCP)增高的阈值及控制颅高压的时机是控制MODS的重要环节。

Objective Discussing the pathogenetic mechanism clinical features and early treatments of infant brain injury complicated with MODS. Methods The data of brain injury under three years old infants complicated with MODS from 2003 to 2007 years were analysed. Results 56 were complicated with MODS among 79 severe brain injury infants （ rate70.88% ）. Conclusion Epilepsy and shock were risk factors for brain injury infants leading to MODS. The key therapy includes effective support of breath and eircu-lation and control of epilepsy. It is also important to treat MODS by reducing intracranial pressure（ ICP）to definite range in time.