HRT视盘参数在原发性开角型青光眼早期诊断中的作用

Ability of the Heidelberg retina tomograph to detect early glaucomatous visual field loss in primary open angle glaucoma

目的:在众多海德堡视网膜断层扫描仪(heidelberg retina tomogragh,HRT)测定的视盘参数中,筛选出最有助于青光眼早期诊断的视盘参数。方法:用HRT测定23例视野损害较轻的青光眼患者和23例正常人的视盘参数(杯盘面积比、盘沿面积、盘沿容积、视杯容积、视杯形态测量、视杯高度变异轮廓和平均神经纤维层厚度)作逐步判别分析。结果:盘沿面积和杯盘面积比对青光眼早期诊断最有帮助,其诊断敏感度和特异度分别为87%和96%。结论:本组资料盘沿面积和杯盘面积比是区分青光眼和正常眼最好的判别因素。

AIM：To select the best optic disc parameters of Heidelberg retina tomogragh（HRT） for the early diagnosis of glaucoma..·METHODS：The optic disc parameters—cup/disk area ratio,rim area,rim volume,cup volume,cup shape measure,height variation contour,and mean retinal nerve fiber layer thickness measured by HRT（version 2.01） were analyzed,and a stepwise discriminant analysis between 23 normal subjects and 23 patients with early glaucomatous visual field loss was performed to determine which parameters were the most informative in detecting individuals with early glaucomatous visual field loss. ·RESULTS：It showed neuroretinal rim area and cup/rim area ratio of all the optic disc parameters were very important in detecting early glaucoma and had a high sensitivity and specificity of 87% and 96%.·CONCLUSION：In all of the optic disc parameters of HRT,rim area and cup/disk area ratio seem to be the best discrimination factors for detecting glaucoma.