糖尿病伴牙周炎患者牙周植骨术的疗效评价

The effect of periodontal operation on type Ⅱ diabetes patients with periodontitis

目的探讨Ⅱ型糖尿病伴牙周炎患者牙周植骨术的临床疗效。方法选择Ⅱ型糖尿病伴牙周炎需植骨患者为实验组,慢性牙周炎需植骨患者为对照组,每组20例。牙周基础治疗3个月后行牙周翻瓣植骨术。检测术前与术后1个月牙龈出血指数、牙周探诊深度、附着丧失水平并拍摄术后4、8、12周平行定位投照片。Ⅱ型糖尿病患者术前及术后3个月测量糖化血红蛋白,术前与术后1个月测量肿瘤坏死因子水平。结果两组38例手术均获成功,失败2例。对照组术后1个月各项临床指标与实验组比较统计学无意义(P>0.05);两组术后较术前各指标明显降低(P<0.001);手术前后肿瘤坏死因子及糖化血红蛋白检测统计学意义(P>0.05)。结论对Ⅱ型糖尿病伴牙周炎患者牙周基础治疗后行牙周植骨手术可取得满意疗效。

Objective To investigate the effect of periodontal operation on type 2 diabetes patients with periodontitis.Methods Twenty healthy adults and Twenty 2 diabetes patients with periodontal intrabony defects were selected. The followings were recorde the 1st month before the operation and repeated at the 1st month after the operations：bleeding index （BI）,probing depth （PD）,the clinical attachment loss （CAL）,circulating tumor necrosis factor-alpha （TNF-α） concentration and the value of glycosylated hemoglobin （HbA1C）.Results There were not significant differences between the two groups （P〉0.05）.Conclusion The periodontal operation is effective to type 2 diabetes patients with periodontitis in the treatment of intrabody defects.