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FOLFOX化疗方案治疗结直肠癌周围神经毒性的观察和护理

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摘要 目的:观察FOLFOX化疗方案治疗结直肠癌的周围神经毒性反应,采取相应的护理措施,为做好结直肠癌患者化疗后神经毒副反应的预防性护理提供依据。方法:对患者出现的神经毒性反应观察及护理措施进行详细的记录和分析,总结在心理、皮肤、血管、饮食护理方面的经验。结果:FOLFOX化疗时,89.7%(70/78)的患者出现周围神经毒性表现,53.8%(42/78)表现为LeviⅠ级,无Ⅳ级发生。自行消失63例,7例经葡萄糖酸钙和硫酸镁静滴后消失。结论:FOLFOX化疗方案治疗晚期结直肠癌过程中,及时观察、预防性护理干预及对症护理可避免或减轻毒性反应,有效地减轻了患者的痛苦,提高了依从性,确保了化疗用药的效果和用药安全。
作者 刘婷
机构地区 沈阳市肛肠医院
出处 《中国当代医药》 2009年第18期102-103,共2页 China Modern Medicine
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