摘要
以1,8-二萘酸酐为原料,经氢化铝锂还原得1,8-二羟甲基萘(2);2经浓盐酸酸化生成1,8-二氯甲基萘(3);3经氢化铝锂还原为1,8-二甲基萘(4);用强碱丁基锂和叔丁醇钾将4转化成二钾盐后与甲氧基氯甲烷反应合成了1,8-二甲氧基乙基萘,其结构经1HNMR和13C NMR和HR-MS表征。
Naphthalic anhydride was reduced to 1,8-bis (hydroxylmethyl) -naphthalene (2) by lithium aluminum hydride, then was treated by concentrated hydrochloric to form 1,8-bis (chloromethyl)naphthalene (3). 3 was reduced to 1,8-dimethylnaphthalene (4) by lithium aluminum hydride again. 4 was transferred to the dipotassium salt of 4 and then directly reaction with chloro(methyl) methane to gain 1,8-bis (2-methoxylethyl) -naphthalene (5). The structures were characterized by 1H NMR, 13C NMR and HR-MS.
出处
《合成化学》
CAS
CSCD
北大核心
2009年第5期634-636,共3页
Chinese Journal of Synthetic Chemistry
关键词
1
8-二羟甲基萘
1
8-二氯甲基萘
1
8-二甲基萘
1
8-二甲氧基乙基萘
合成
1,8-bis ( hydroxylmethyl ) naphthalene
1,8-bis ( chloromethyl ) naphthalene
1,8-dimethylnaphthalene
1,8-bis(2-methoxylethyl)-naphthalene
synthesis