颅内单发纤维性肿瘤临床病理及影像学表现

Clinical and Imaging Manifestations of Intracranial Solitary Fibrous Tumors

目的:分析颅内单发性纤维性肿瘤的临床、病理及影像学特点,提高对该病的认识。方法:3例经手术、病理证实的颅内单发性纤维性肿瘤,临床主要表现为头痛、恶心、呕吐,下肢无力等症状,结合文献分析颅内单发性纤维性肿瘤临床、病理及影像学表现。结果:在MRI上,2例肿瘤实性部分表现为在T1WI上呈等、低混杂信号,T2WI上呈高、低混杂信号,肿瘤内可见囊变区,1例T1WI上呈高信号,MRI增强病变明显不均匀强化,周围伴有水肿,相邻侧脑室受压,中线结构移位。结论:颅内单发性纤维性肿瘤是一种少见疾病,仅靠影像学表现作出诊断较为困难,需结合临床症状和病理综合分析,作出准确的诊断。

Objective：To investigate the clinical and imaging characteristics of intracranial solitary fibrous tumors,so as to improve the understanding of this disease entity.Methods：3 patients had surgery and pathology proved intracranial solitary fibrous tumor.The main clinical manifestations included headache,nausea,vomiting and lower limb weakness.The clinical,pathological and imaging materials were analyzed and the relative literatures were reviewed.Results：On MRI,the solid part of the mass showed iso-and hypo-intensity on T1WI and heterogeneous hyper-and hypo-intensity on T2WI with intra-tumoral cystic area in 2 cases.In another case,the tumor showed hyper-intensity on T1WI,marked heterogeneous enhancement after contrast administration,peri-tumoral edema,compression of adjacent ventricle and displacement of mid-line structure.Conclusion：Intracranial solitary fibrous tumors is a rare disease entity,it is difficult to make an accurate diagnosis only depend on imaging features,comprehensive analysis including clinical symptoms and pathology should be undertaken.