舌和口底鳞状细胞癌和脉管畸形的MR-DWI评价

Squamous Cell Carcinoma and Vascular Malformation in the Tongue and the Floor of the Mouth:Evaluation with MR Diffusion-weighted Imaging(MR-DWI)

目的:评价舌和口底鳞状细胞癌(SCC)和脉管畸形的MR扩散加权成像(MR-DWI)特点。方法:对治疗前行常规MRI和MR-DWI检查的65例舌和口底SCC和11例脉管畸形(均经手术病理证实)进行回顾性分析。MR-DWI上,分别于b值为500 s/mm2和1000 s/mm2时获取其ADC均值,并进行t检验统计处理和分析。结果:b值分别为500 s/mm2和1000 s/mm2时,SCC的ADC均值分别为1.23×10-3mm2/s和0.904×10-3mm2/s;脉管畸形的ADC均值分别为1.79×10-3mm2/s和1.17×10-3mm2/s。统计分析显示两组b值情况下的ADC均值在SCC和脉管畸形之间差异均有统计学意义(P<0.01)。结论:舌和口底SCC和脉管畸形之间具有不同MR-DWI特点,两者之间的差异能为临床鉴别诊断提供有益信息。

Objective：The study aimed at evaluating MR diffusion-weighted imaging（MR-DWI） features of squamous cell carcinoma（SCC） and vascular malformation in the tongue and the floor of the mouth.Methods：We retrospectively observed seventy-six lesions（65 SCCs and 11 vascular malformations） in the tongue and the floor of the mouth,which had undergone both conventional MR imaging and MR-DWI prior to surgery and pathologic examination.The mean ADC from both b values（500 and 1000s/mm^2） were calculated and correlated with the pathologic results.A student t test was used to statistically compare the diversities of mean ADC between SCC and vascular malformation.Results：The mean ADC in SCCs obtained from b values of 500s/mm^2 and 1000s/mm^2 was 1.23×10^-3mm^2/s and 0.904×10-3mm^2/s,respectively.The mean ADC in vascular malformations obtained from b values of 500s/mm^2 and 1000s/mm^2 was 1.79×10^-3mm^2/s and 1.17×10^-3mm^2/s,respectively.Statistically,there was significant differences between both lesions（P〈0.01）.Conclusion：Different features between SCC and vascular malformation in the tongue and mouth floor are able to be identified with MR-DWI,which may provide valuable information in discrimination of both lesions for clinical diagnosis.