研制蜂胶冻干粉的最佳工艺研究

Research on the best preparation of lyophilized propolis

本文探讨了以粗蜂胶为原料,研制蜂胶冻干粉的的工艺。结果表明:蜂胶冻干粉的工艺流程为粗蜂胶─→醇溶法提取─→赋形─→冻干─→冻干粉。最佳工艺条件为:(1)醇溶法提取蜂胶的最佳条件:固液比:1:25,乙醇溶液浓度75%,提取温度80℃,提取时间1.5h。(2)赋形剂为22%甘露醇,赋形的最佳条件为:22%甘露醇与4%的蜂胶乙醇溶液按76:24的比例混合。(3)冻干条件:预冻温度-74℃,预冻时间2小时,抽真空时间24小时,升温干燥20℃,升温干燥30分钟,冷阱温度为-52℃。在此条件下生产的蜂胶冻干粉的溶解度为87%,水分含量为0.93,总黄酮含量为0.49%。

This paper deals with the preparation of lyophilized propolis powder which uses the crude propolis as raw materials. The results showed ： the process of lyophilized propolis powder is crude propolis → ethanol extraction → shaped → lyophilized → lyophilized powder. Optimum conditions ： （1） the best conditions of ethanol Extraction Propolis ： the ratio ： 1：25 ,ethanol concentration： 75% ,extraction temperature： 80℃, extraction time 1.5. （2） The excipient is mannitolof 22%, the best conditions of given the shape ： using 22% manrtitol propolis which is mixed by 24：76 ratio （3） Freeze-drying conditions ： after two hours -74~C freezing puts them in the vacuum for 24 hours and warm and dry at 20℃ for 30 minutes. The cooling temperature is -52℃. Under this condition, the solubility of lyophilized propolis powder is 87% and moisture content of 0.93%, Flavonoids content is 0.49%.