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蛛网膜下腔出血患者ATⅢ、PAI活性变化及其与CVS关系的研究

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摘要 目的动态观察蛛网膜下腔出血(SAH)患者的血液和脑脊液(CSF)中抗凝血酶Ⅲ(ATⅢ)、组织纤溶酶原激活物抑制物(PAI)活性,并探讨二者与SAH后脑血管痉挛(CVS)之间的关系。方法收集60例SAH患者3 d内及5-7 d的外周静脉血和CSF,采用发色底物法测定ATⅢ及PAI。结果CVS组SAH患者血浆和CSF中ATⅢ下降幅度、PAI升高幅度均较无CVS组明显(P〈0.05)。结论ATⅢ、PAI活性变化与CVS密切相关。
出处 《山东医药》 CAS 北大核心 2009年第36期66-67,共2页 Shandong Medical Journal
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